Abstract
Therapy of antiphospholipid syndrome (APS) is a lifelong primary and secondary prophylaxis of thromboses. Due to appearance of new anticoagulants question of antithrombotic therapy choosing became more complicated. Optimization of anticoagulants selection at APS according pathogenesis, existing risk factors and comorbidity is discussed. Advantages and indications for regular monitoring of plasma anti-Xa activity at patients with primary and secondary APS are presented.
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