Do minor dental interventions affect hemostasis and acetylsalicylic acid safety in patients with hypertensive small deep cerebral infarctions? 616-08-031.84:616.314-74:615.036

Abstract

Summary. Introduction. Patients taking antiplatelet therapy often need dental interventions. Aim: to evaluate acetylsalicylic acid (ASA) safety for small dental interventions in patients with hypertensive small deep cerebral infarctions (SDCI). Materials and Methods. The observational prospective study included 62 patients with hypertensive SDCI. Treatment and extraction of one or more teeth were carried in the first 24–48 hours after lacunar stroke. Before dental intervention all patients have taken hypotensive therapy, ASA (75 mg/day) and statins. Platelet aggregation and hemostasis parameters screening performed in all patients as well. Results. All hypertensive SDCI patients had high intensity of caries process, middle risk degree of chronic oral sepsis and middle level of chronic generalized periodontitis, those were reduced by 2.4–4.2 times after professional oral hygiene, treatment and tooth extraction at the end of in-hospital time. No hemostatic parameters abnormalities and increased blood loss associated with ASA were registered. Conclusion. Small dental interventions do not affect hemostasis and ASA safety in patients with hypertensive SDCI.

For citation: Maksimova M.Yu., Tanashyan M.M., Ryazantsev N.A., Anisimova E.N., Shabalina A.A. Do minor dental interventions affect hemostasis and acetylsalicylic acid safety in patients with hypertensive small deep cerebral infarctions? Tromboz, gemostaz i reologiya. 2023;(4):75–82. (In Russ.).

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