Clinical case of Rendu–Osler–Weber disease in a pregnant woman: 616-005.1:616.151.5

Abstract

Summary. The article describes a case of Rendu–Osler–Weber disease, a rare condition caused by genetically determined anatomical and functional changes in blood vessels. These changes include absence or degeneration, hypoplasia and dysplasia of the muscular and elastic membranes. This case is unique due to the disease being present in a pregnant woman. This paper includes the patient’s medical history from childhood, as well as data from laboratory and instrumental examinations conducted in the hospital. Additionally, the paper covers the management of childbirth and anesthesia, taking into account the patient’s medical condition. A comprehensive examination of hemostasis and the pathogenetically justified use of medications made it possible to avoid radiation exposure from instrumental research methods and to choose a safe, optimal method of delivery and anesthesia for this patient.

For citation: Bulanova E.L., Rabotinsky S.E., Sizova I.Yu., Osokin I.P., Sheina M.A. Clinical case of Rendu–Osler–Weber disease in a pregnant woman. Tromboz, gemostaz i reologiya. 2024;(2):76–81. (In Russ.).

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