Тромбоз, гемостаз и реология

Tromboz, Gemostaz I Reologiya
scientific and practical journal

ISSN 2078–1008 (Print); ISSN 2687-1483 (online)
2024, Original papers
2024

Hematological parameters in patients with internal carotid artery atherosclerotic stenosis during tooth extraction: 616‐08‐031.84:616.314‐74:615.036

Original papers
Published 2024-10-11
Marine M. Tanashyan
Research Center of Neurology; 80 Volokolamskoe Shosse, Moscow 125367, Russia; Russian University of Medicine, Ministry of Health of the Russian Federation; 4 Dolgorukovskaya Str., Moscow 127006, Russia
ФГБНУ «Научный центр неврологии»; Россия, 125367, Москва, Волоколамское шоссе, 80; ФГБОУ ВО «Российский университет медицины» Министерства здравоохранения Российской Федерации; Россия, 127006 Москва, Долгоруковская ул., 4
https://orcid.org/0000-0002-5883-8119 (unauthenticated)
Marina Yu. Maksimova
Research Center of Neurology; 80 Volokolamskoe Shosse, Moscow 125367, Russia; Russian University of Medicine, Ministry of Health of the Russian Federation; 4 Dolgorukovskaya Str., Moscow 127006, Russia
ФГБНУ «Научный центр неврологии»; Россия, 125367, Москва, Волоколамское шоссе, 80; ФГБОУ ВО «Российский университет медицины» Министерства здравоохранения Российской Федерации; Россия, 127006 Москва, Долгоруковская ул., 4
https://orcid.org/0000-0002-7682-6672 (unauthenticated)
Eugene V. Roitman
Research Center of Neurology; 80 Volokolamskoe Shosse, Moscow 125367, Russia;
ФГБНУ «Научный центр неврологии»; Россия, 125367, Москва, Волоколамское шоссе, 80;
https://orcid.org/0000-0002-3015-9317 (unauthenticated)

Keywords

internal carotid artery atherosclerotic stenosis
ICS
tooth extraction
acetylsalicylic acid
ASA
hematological parameters
  Full Text

Abstract

Summary. Introduction. The foundation of acute cerebrovascular event prevention in patients with internal carotid artery (ICA) atherosclerosis is a continuous antiaggregant therapy. Aim: to study changes in the nature of hematological status during tooth extraction in patients with ICA atherosclerotic stenosis without discontinuation of acetylsalicylic acid (ASA). Materials and Methods. A prospective comparative study was conducted. The examination was conducted 2 hours and 48 hours after tooth extraction in 34 patients with ICA atherosclerotic stenosis, which included the evaluation of the main parameters of vital signs (blood pressure, heart rate, body temperature, adequacy of oxygenation), parameters of a general blood test and coagulogram, D‐dimer and von Willebrand factor levels. Results. Two hours following tooth extraction, an increase in fibrinogen and von Willebrand factor levels was noted accompanied by a decrease in activated partial thromboplastin time, prothrombin time, and thrombin time. These changes were observed to return to baseline levels after 48 hours. Conclusion. In patients with ICA atherosclerosis, a continuous regimen of ASA use is essential for the safe and effective tooth extraction.

For citation: Tanashyan M.M., Maksimova M.Yu., Roitman E.V. Hematological parameters in patients with internal carotid artery atherosclerotic stenosis during tooth extraction. Tromboz, gemostaz i reologiya. 2024;(3):51–57. (In Russ.).

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